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The Women’s Health InitiativeWHIestrogen-alone substudy reported increased risks of stroke and deep vein thrombosisDVTin postmenopausal women with daily oral conjugated estrogensCEaloneThe WHI estrogen-plus-progestin substudy reported increased risks of DVTpulmonary embolismstrokeand myocardial infarction in postmenopausal women with daily oral CE combined with medroxyprogesterone acetateMPAIn the absence of comparable datathese risks should be assumed to be similar for other dosage forms of estrogens.
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Estrogen treatment of prepubertal children also induces premature breast development and vaginal cornificationand may potentially induce vaginal bleeding in asthma inhaler no prescription, asthma inhaler no prescription, asthma inhaler no prescription, asthma inhaler no prescription, asthma inhaler no prescription, asthma inhaler no prescription. girlsIn boysestrogen treatment may modify the normal pubertal processAll other physiological and adverse reactions shown to be associated with estrogen treatment of adults could potentially occur in the pediatric populationincluding thromboembolic disorders and growth stimulation of certain tumorsThereforeestrogens should only be administered to pediatric patients when clearly indicated and the lowest effective dose should always be utilized.
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