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Patients with these symptoms should be screened for papilledema and, if present, the patients should be advised to discontinue vero-danazol immediately and be referred to a neurologist for further diagnosis and care.
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In most instancesbreast pain and tenderness are significantly relieved by the first month and eliminated in 2 to 3 monthsUsually elimination of nodularity requires 4 to 6 months of uninterrupted therapyRegular menstrual patternsirregular menstrual patternsand amenorrhea each occur in approximately one-third of patients treated with 100 mg of DanazolIrregular menstrual patterns and amenorrhea are observed more frequently with higher dosesClinical studies have demonstrated that 50of patients reputable canadian distributors. may show evidence of recurrence of symptoms within one yearIn this eventtreatment may be reinstated.
Anti-Convulsant Therapydanazol may affect the plasma level of carbamazepine andpossibly the patient’s response to this agent and to phenytoinWith phenobarbital it is likely that similar interaction would occur.
Preliminary epidemiological evidence suggests that the use of danazol might increase the baseline risk of ovarian cancer in patients being treated for endometriosis.
Backache and muscle cramps which can be severeCreatine phosphokinase levels may also riseMuscle tremorsfasciculationlimb painjoint pain and joint swelling have also been reported.
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