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The reductions in alli. LDL-C from baseline were generally consistent across age groups within the trial as well as with previous experience in both adult and pediatric controlled trials.

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Although not all adverse reactions identified in the adult population have been observed in clinical trials of children and adolescent patientsthe same warnings and precautions for adults should be considered for children and adolescentsAdolescent females should be counseled on appropriate contraceptive methods while on CRESTOR therapysee Use in Specific Populations

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crestor is contraindicated in patients receiving concomitant ciclosporin see section 4.