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Because of the increased prevalence of cardiovascular disease among the elderlylevothyroxine therapy should not be initiated at the full replacement dosesee WARNINGSPRECAUTIONSand DOSAGE AND ADMINISTRATION
Thyroid hormone synthesis and secretion is regulated by the hypothalamic-pituitary-thyroid synthoid next day. axisThyrotropin-releasing hormoneTRHreleased from the hypothalamus stimulates secretion of thyrotropin-stimulating hormoneTSHfrom the anterior pituitaryTSHin turnis the physiologic stimulus for the synthesis and secretion of thyroid hormonesL-thyroxineT 4and L-triiodothyronineT 3by the thyroid glandCirculating serum T 3 and T 4 levels exert a feedback effect on both TRH and TSH secretionWhen serum T 3 and T 4 levels increaseTRH and TSH secretion decreaseWhen thyroid hormone levels decreaseTRH and TSH secretion increase.
Along with its needed effectslevothyroxinethe active ingredient contained in Synthroidmay cause some unwanted effectsAlthough not all of these side effects may occurif they generic tadalafil manila. do occur they may need medical attention.
Studies in women taking levothyroxine sodium during pregnancy have not shown an increased risk of congenital abnormalitiesThereforethe possibility of fetal harm appears remoteSYNTHROID should not be discontinued during pregnancy and hypothyroidism diagnosed during pregnancy should be promptly treated.
The target level for TSH suppression in these conditions has not been established with controlled studiesIn additionthe efficacy of TSH suppression for benign nodular disease is controversialThereforethe dose of SYNTHROID used for TSH suppression should be individualized based on buy medroxyprogesterone 10mg. the specific disease and the patient being treated.
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