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The recommended total daily dose of topamax as adjunctive therapy in adults with partial onset seizures or lennox-gastaut syndrome is 200 to 400 mg day in two divided doses, and 400 mg day in two divided doses as adjunctive treatment in adults with primary generalized tonic-clonic seizures.
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the possibility of decreased contraceptive efficacy and increased breakthrough bleeding may occur in patients taking combination oral contraceptive products with topamax.