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I have been taking pristiq for about 2 years now and find i am good on them , at first i wasn t sleeping i was sitting up all night and that was making me feel so drawn out, the doctor suggested i take them at night, so now i take them at 8pm each night and i am sleeping, not 8 hours but at least i am getting some, around 6 hours it varies.
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if pristiq is poorly tolerated, every other day dosing can be considered.