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Catecholamine depleting drugse.greserpinemonoamine oxidaseMAOinhibitorsmay have an additive effect when given with beta-blocking agentsObserve patients treated with TOPROL-XL plus a catecholamine depletor for evidence of hypotension or marked ventolin without prescription. bradycardiawhich may produce vertigosyncopeor postural hypotension.
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the relationship between plasma metoprolol levels and reduction in exercise heart rate is independent of the pharmaceutical formulation.